Haemophilus influenzae type b (Hib) is an encapsulated bacterium which can cause a range of conditions including meningitis, septicaemia and pneumonia. Hib infections were a major cause of bacterial meningitis in children under the age of 5 until vaccinations with the protein-conjugated Hib vaccine were introduced.

The Hib vaccine is conjugated to a protein in order to elicit an immune response in healthy infants whose immune system is still developing. It is important to remember that a protein conjugated polysaccharide vaccine such as the Hib vaccine behaves physiologically like a protein antigen such as Tetanus toxoid.

This assay is therefore intended to measure the level of specific anti Hib total IgG in serum. Microwells are coated with the Hib capsular polysaccharide antigen conjugated to human serum albumin.

Haemophilus influenzae Type B (Hib) Kit

Each kit includes prediluted calibrator sets, high and low controls, HRP conjugated antibodies, sample diluents, TMB substrate, stop solution and wash buffer.

VaccZyme™ is a trademark of The Binding Site Group Ltd, Birmingham, UK.