Tetanus toxoid Assays for immune status or response to vaccination
IgG antibodies to Tetanus toxoid are produced by the immune system following infection with C.tetani (in response to the presence of the toxin), or in response to immunisation with a Tetanus vaccine. The measurement of specific IgG antibodies to Tetanus toxoid pre-vaccination and post-vaccination is important in the assessment of the individual's ability to elicit an immune response to protein antigens. This assay may also be used to determine the immune status of the individual with respect to Tetanus infection.
ELISA / EIA for quantitation of Tetanus toxoid IgG
Microwells are coated with Tetanus toxoid. 96 well kits are available to measure the specific IgG or the IgG1 levels in serum. The standard ELISA format enables easy automation of this assay.
| Tetanus toxoid | Measuring Range | Analytical Sensitivity |
| IgG | 0.01 - 7 IU/mL | 0.01 IU/mL |
| IgG1 | 0.67 - 54 mg/L | 0.3 mg/L |
| Description | Pack | Code |
|---|---|---|
| VaccZyme™ Tetanus toxoid IgG* | 96 test | MK010 |
| Tetanus toxoid IgG1** | 96 test | MK011 |
* Please enquire regarding FDA status
** Research use only
A turbidimetric tetanus toxoid assay is also available on the SPAPLUS analyser.
For Plasma Screening and Intravenous Immunoglobulin production, Tetanus toxoid IgG assays with higher measuring ranges are available.
- Download literature - Tetanus Toxoid IgG - Code MKG294.1
- Download FRENCH literature - Tetanus Toxoid IgG - Code MKG377
VaccZyme™ is a trademark of The Binding Site Group Ltd, Birmingham, UK
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