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Home> Products> Instrumentation> SPAplus Specialist Protein Analyser
SPAplus Specialist Protein Analyser
   

spaplus specialist protein analyser logoCompact Automated Analyser for Specialist Protein Analysis

spaplus specialist protein analyser

The SPAplus analyser has been exclusively developed for Binding Site Specialist Protein Assays.

The SPAplus is a compact, turbidimetric platform. It is fully automated enabling laboratories to maintain the quality of results and high throughput required for specialised protein assays. It can be placed alongside the laboratory’s main-line analysers or in other areas of the laboratory.

Pre-programmed protocols developed and manufactured by Binding Site provide highly sensitive and reproducible results that match or have greater sensitivity than nephelometry. The modular design with intuitive Windows® based software makes the SPAplus very easy to use. It is engineered to a high standard demonstrating excellent reliability with minimal daily, weekly and monthly maintenance procedures.

The SPAplus assay menu includes Freelite® serum free light chain assays, Hevylite® heavy chain/light chain assays, IgG and IgA subclasses plus a complement panel featuring CH50. Newly launched CSF (cerebrospinal fluid) assays (IgG, IgA, IgM and albumin) further enhance the expanding assay range on SPAplus.

Confidence

  • Automatic sample dilution (1/10 - 1/100; assay specific) – minimises hands-on time
     
  • Automatic low and high rerun of out-of-range samples (dilutions available from neat - 1/100; dilution is assay-specific)
     
  • Automatic antigen excess detection for Freelite® assays enables all samples to be run in singleton whilst ensuring all antigen excess samples are identified.
     
  • Internal QC program with Levy-Jennings graphing giving confidence in results
     
  • Onboard reagent storage; reagents cooled to 10 + 2ºC – no need to transfer reagents in and out of refrigerator
     
  • Sample ID and Reagent barcode recognition for ease of sample and reagent loading
     
  • Sample and reagent level detection ensures integrity of sample
 spaplus specialist protein analyser

Easy to Use

  • Intuitive Windows® based software
     
  • Bidirectional interface capability
     
  • 24 reagent positions with automatic reagent changeover
     
  • Automatic calculation of the Freelite® κ/λ ratio

Speed & Productivity

  • Up to 120 tests per hour
     
  • Automated rerun and dilution minimising loading time
     
  • Walk-away capacity for 45 samples per tray
     
  • Automatic washing, liquid level sensing probes
     
  • Separate sample, R1 reagent and R2 reagent probes – minimising carry over
     
  • Run monitor displays waiting time

Built-In Reliability

  • spaplus curvettesLow user maintenance
     
  • Mean Time Between Failure: 360 days
     
  • Unique dual chamber cuvette
     
  • Unique contact-free air-pressure mixing minimises carry-over
     
  • High temperature cuvette wash to extend cuvette life
     
  • Long life acrylic cuvettes minimise replacement costs
     
  • Automatic cuvette flagging when replacement is required
     
  • Modular design for easy maintenance

Throughput

  • Up to 120 tests/hr
     
  • 10 minute assay incubation - 15 minutes to first result - every 30 seconds thereafter

Reagent Module

  • 24 reagent positions
     
  • Onboard reagent cooling (10°C + 2°C)
     
  • Dual reagent probes with automated washing between reagent addition
     
  • Reagent level detection and reagent management
     
  • Automatic reagent changeover

Sampling Module

  • Sample Type: serum, plasma, urine
     
  • 40 sample + 5 STAT positions per carousel: 30 primary/secondary tube with barcode reading
     
  • Sample tubes accepted: disposable cups, secondary tubes, 5mL, 7mL, 10mL primary tubes
     
  • Integrated sample barcode reader. Acceptable Bar Codes: Code 39, Code 128, ITF, NW-7. Reads up to 18 digits.
     
  • Sample volume: 3-30µL, minimum sample volume (cups/secondary tubes) 150 µL
     
  • Automatic sample dilution
     
  • Automatic rerun
     
  • Sample level detection
     
  • Automatic interior/exterior sample probe washing

Reaction Module

  • 60 semi-permanent acrylic cuvettes
     
  • Reaction temperature 37°C + 0.1°C
     
  • Automatic 10-step, high temperature cuvette washing system
     
  • Dual-chamber, air pressure enhanced mixing

Optics Module

  • Wavelength: 12 discrete
     
  • Automatic cell blank monitoring
     
  • Halogen lamp: 2000 hours with lamp-life monitor
     
  • Silicon photo-diode detectors

Software

  • Windows®-based
     
  • LIS compatible (RS-232C bi-directional interface)
     
  • Levy-Jennings QC monitoring
     
  • Water supply, wash solutions and waste level alarms

Physical Specifications

  • Dimension: 31.5"/800mm (Width) x 25.2"/640mm (Depth) x 20.5"/520mm (Height)
     
  • Weight: 210 lbs / 96kgs
     
  • Power requirements: AC 100/115/230 V 50/60 Hz
     
  • Rated power consumption: 600 VA
     
  • Water type: Deionised Water
     
  • 3L Acid and 3L Alkali wash bottles
     
  • 10L DI water reservoir, 10L waste container and 5L back-up waste and water containers

Maintenance Service

  • 1-year limited service warranty
     
  • Minimal user maintenance

 

Description
Pack
Code
Freelite® Kappa Latex SPAplus kit
Range 4-180 mg/L (1/10)
Range 40-1800 mg/L (1/100)
Sensitivity 0.4 mg/L		 100 test LK016.S
Freelite® Lambda Latex SPAplus kit
Range 4.5-165 mg/L (1/10),
Range 45-1650 mg/L (1/100)
Sensitivity 0.45 mg/L
100 test
LK018.S
Hevylite® IgG Kappa SPAplus kit
Range 1.9 - 40.0 g/L (1/20),
Sensitivity 0.09 g/L		 50 test NK621.S
Hevylite® IgG Lambda SPAplus kit
Range 0.92 - 29.50 g/L (1/20),
Sensitivity 0.046 g/L		 50 test NK622.S
Hevylite® IgA Kappa SPAplus kit
Range 0.18-11.2 g/L (1/10),
Sensitivity 0.018 g/L		 50 test NK623.S
Hevylite® IgA Lambda SPAplus kit
Range 0.16 - 10.4 g/L (1/10),
Sensitivity 0.016 g/L		 50 test NK624.S
Hevylite® IgM Kappa Latex SPAplus kit
Range 0.2 - 5.0 g/L (1/10),
Sensitivity 0.02 g/L		 50 test NK625.S
Hevylite® IgM Lambda Latex SPAplus kit
Range 0.18 - 4.5 g/L (1/10),
Sensitivity 0.018 g/L		 50 test NK626.S

 

IgG SPAplus kit
Range 1650-35000 mg/L (1/10)
Sensitivity 165 mg/L                                      		  100 test NK004.S
IgA SPAplus kit
Range 200-7000 mg/L (1/10)
Sensitivity 20 mg/L		  100 test  NK010.S
IgM SPAplus kit
Range 200-7500 mg/L (1/20)
Sensitivity 100 mg/L		  100 test  NK012.S
IgD SPAplus kit
Range 7 - 210 mg/L (1/10)
Sensitivity 7 mg/L		  100 test  LK013.S
IgG1 SPAplus kit
Range 1500-36000 mg/L (1/10)
Sensitivity 150 mg/L		  100 test  NK006.S
IgG2 SPAplus kit
Range 200-7000 mg/L (1/10)
Sensitivity 20 mg/L		 100 test NK007.S
IgG3 SPAplus kit
Range 55-1000 mg/L (1/10)
Sensitivity 5.5 mg/L		 100 test LK008.S
IgG4 SPAplus kit
Range 30-850 mg/L (1/10)
Sensitivity 3 mg/L		 100 test LK009.S
IgA1 SPAplus kit
Range 300-6000 mg/L (1/10)
Sensitivity 30 mg/L		 50 test NK087.S
IgA2 SPAplus kit
Range 50 - 1250 mg/L (1/10)
Sensitivity 5.0 mg/L		 50 test LK088.S

 

C3c SPAplus kit
Range 250 - 3000 mg/L (1/10)
Sensitivity 250 mg/L                                         		  100 test NK023.S
C4 SPAplus kit
Range 64 - 900 mg/L (1/10)
Sensitivity 6.4 mg/L		  100 test NK025.S
NEW C1 Inactivator SPAplus kit
Range 0.03 - 0.04 g/L (1/10)
Sensitivity 0.075 g/L		 50 test NK019.S
CH50 SPAplus kit
Range 12 - 95 U/mL (1/1)
Sensitivity 12 U/mL		  200 test NK095.S
CH50 Controls for SPAplus
5 x High control, 5 x Low control		 1 set NQ095.S
CH50 Calibrators for SPAplus 1 set NC095.S

 

NEW Albumin serum SPAplus kit
Range 2.9 - 92.4  g/L (1/30)
Sensitivity 0.1 g/L		 100 test NK032.S
NEW Albumin CSF SPAplus kit
Range 170-2700  mg/L (1/10)
Sensitivity 17 mg/L		 60 test NK032.L.S
Beta-2 Microglobulin Latex SPAplus kit
Range 0.6-20 mg/L (1/20)
Sensitivity Serum 0.3 mg/L (1/10)
Sensitivity Urine 0.03 mg/L (1/1)		 100 test LK043.S
Cystatin C Latex SPAplus kit
Range 0.4-7.35 mg/L (1/10)
Sensitivity 0.14 mg/L		 100 test LK048.S
NEW Haptoglobin SPAplus kit
Range 0.26 - 4.0 g/L (1/10),
Sensitivity 0.026 g/L		 100 test NK058.S
NEW IgG CSF SPAplus kit
Range 4-135 mg/L (1/1)
Sensitivity 4.0 mg/L		 60 test NK004.L.S
NEW IgA Latex CSF SPAplus kit
Range 200-7000 mg/L (1/10)
Sensitivity 0.15 mg/L		 60 test LK010.L.S
NEW IgM Latex CSF SPAplus kit
Range 0.3-7 mg/L (1/1)
Sensitivity 0.3 mg/L		 60 test LK012.L.S
NEW Prealbumin SPAplus kit
Range 0.06 - 0.66 g/L (1/10),
Sensitivity 0.006 g/L		 100 test NK066.S

Tetanus toxoid Latex SPAplus kit
Range 1.56 - 50 IU/mL (1/10)
Sensitivity 1.56 IU/mL

 1000 test LK710.S
NEW Transferrin
Range 0.14 - 5.6 g/L (1/10)
Sensitivity 0.075 g/L		 100 test NK070.S

*In development for 2012:

  • Albumin Urine
  • Alpha 1 Acid Glycoprotein
  • Alpha 1 Antitrypsin
  • Alpha 2 Macroglobulin
  • Anti-Streptolysin O
  • C2
  • Caeruloplasmin
  • CRP & High Sensitivity CRP
  • Rheumatoid Factor
  • Secretory IgA

SPAplus is currently available in UK, USA, Canada, France, Germany, Austria, Spain, Czech Republic, Slovak Republic, Belgium, Netherlands, Luxembourg and Italy. In other countries please contact your local Binding Site supplier.

Windows is a registered trademark of The Microsoft Corporation.
 

AUTODIL 100

The AUTODIL 100 has been designed to complement the SPAplus system and offers a labour saving solution for creating offline dilutions that are occasionally required in conjunction with Freelite®assays.

The AUTODIL 100 is a compact, automatic dilutor with simple functionality that creates 1/100 dilutions of serum samples. With a combination of a high quality 1mL syringe and electronic stepping motor this instrument is ideal for increasing the precision and accuracy each time offline 1/100 dilutions are performed.

Technical Specification

Dimensions

  • Height 275mm x Width 125mm x Depth 210mm
  • Weight 4.6kg
 
Power requirements
  • 115 - 230V AC
  • 50 - 60Hz
  • 30VA
Description Pack Code
AUTODIL 100 1 IE650
AUTODIL 100 Sample Diluent 1 x 250 mL SN119

 Other Accessories

Description Pack Code
SPAplus Acid Washing Solution 500mL SP2209
SPAplus Alkaline Washing Solution 500mL SP2208
SPAplus Calibrator Rack - Direct Load 1 IK530
SPAplus Data Extractor 1 IK550
SPAplus Halogen Lamp 1 SP2057
SPAplus Reaction Cuvettes 60 20-07-0126
SPAplus Reagent Tray 1 20-06-0110
SPAplus Sample Cups 1000 TBS043
SPAplus Sample Diluent 6 SN080.S
SPAplus Sample Diluent 2 3 SN114.S
SPAplus Universal Tube Elevators 30 IK520
SPAplus Weekly Wash Protocol & Bottles 6 IK050.S

Accessories in development for 2012:

  • Control rack direct load
  • Calibrator and control lid rack