Vaccine Response Enzyme Immunoassays
Failure of the immune system to produce the appropriate antibody response to infection, or the production of functionally inactive antibodies, may result in recurrent or persistent infections.
Measurement of antigen specific immunoglobulins, pre-immunisation and post-immunisation with an appropriate vaccine, aids in the identification of:
- Selective IgG subclass deficiencies
- Primary antibody deficiencies
- Delayed maturation of the immune system
Assessment of both IgG subclass antibody concentrations and the immune response to both protein and polysaccharide vaccines during the investigation of possible primary immunodeficiency will assist in offering more comprehensive information to the clinician and may aid in the diagnosis of primary immunodeficiency (PID).
The vaccine response ELISA (Enzyme-linked immunosorbent assay) kits use the 96 well plate format (12 x 8 well strips) and contain ready to use calibrators, controls and conjugates. Standard protocols enable easy automation.
- Tetanus toxoid
- Diphtheria toxoid
- Pneumococcal capsular polysaccharide
- Haemophilus influenzae type b
- Salmonella typhi Vi
- Quality Assurance
- Assays for plasma protein therapeutics industry
VZV glycoprotein ELISA
The new, highly sensitive (10 mIU/mL) VZV glycoprotein IgG ELISA utilises purified glycoprotein antigens. This offers greater specificity and physiological relevance than assays using extracts from VZV infected cultured cells.
Binding Site are market leaders in quantitative IgG Subclass assays and also supply other infectious disease assays (in the UK and USA only).
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