Anti Cardiolipin IgGAM S Screening Kit

Autoantibodies against cardiolipin are found in a wide range of conditions such as systemic lupus erythematosus (SLE) and antiphospholipid syndrome (APS). This kit is designed for the qualitative screening of IgG, A and M autoantibodies against cardiolipin present in human serum. Samples testing positive in this screening assay should be confirmed by a quantitative measurement of the individual classes (IgG, IgA and IgM) of anticardiolipin autoantibody, using e.g. BINDAZYME Anticardiolipin IgG, IgA and IgM S kits.

Antigen

The microwells are precoated with purifed bovine cardiolipin together with human and bovine ß2 glycoprotein-1 (cofactor).

Result Interpretation

ResultInterpretationAction

OD equal to, or greater than cut-off control

 

Suspected of having one or a combination

of anticardiolipin antibodies

Test on each of the quantitative assays

 

OD less than cut-off controlNegativeReport as negative

 

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